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What characterizes irritant contact dermatitis due to latex exposure?

  1. Immediate systemic reaction

  2. Delays in response to exposure

  3. Localized dry or itchy area of contact

  4. Formation of systemic antibodies

The correct answer is: Localized dry or itchy area of contact

Irritant contact dermatitis due to latex exposure is characterized by localized dry or itchy areas of the skin where the latex comes into contact. This type of dermatitis is a non-allergic reaction that can occur in response to irritants, such as the proteins found in latex gloves or other latex products. In this case, the skin's barrier is compromised or damaged, leading to inflammation and irritation without the involvement of the immune system. Symptoms can include redness, dryness, and itching specifically in the areas that contacted latex. This localized response distinguishes it from allergic reactions that may present with systemic symptoms or more widespread skin involvement. The other options involve different mechanisms or types of reactions. For instance, an immediate systemic reaction typically aligns more closely with allergic reactions rather than irritant dermatitis. Delays in response to exposure might suggest allergic contact dermatitis, where the immune system slowly responds to the allergen, and the formation of systemic antibodies relates to true latex allergies rather than irritant reactions. Thus, option C accurately captures the localized nature of irritant contact dermatitis caused by latex exposure.