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What is one common adverse effect associated with the use of succinylcholine?

  1. Hypotension

  2. Fasciculations

  3. Bradycardia

  4. Constipation

The correct answer is: Fasciculations

Succinylcholine is a depolarizing neuromuscular blocker commonly used in anesthesia for rapid sequence intubation. One of the notable adverse effects associated with its use is fasciculations, which are brief, spontaneous muscle contractions. These contractions typically occur after the administration of succinylcholine due to its mechanism of action, which causes initial depolarization of the motor end plate before facilitating neuromuscular blockade. Fasciculations can lead to muscle soreness if they are extensive, and their presence is often a diagnostic indicator that succinylcholine has taken effect. Understanding the mechanism behind these fasciculations is critical for anesthesia professionals as it helps in anticipating patient responses and managing any associated complications during the administration of this medication. The other options—hypotension, bradycardia, and constipation—are not commonly associated with succinylcholine. While succinylcholine can sometimes be linked to dysrhythmias or changes in heart rate, the more immediate and recognized effect is the occurrence of fasciculations shortly after administration.